Brand names of Tamoxifen are following: Novaldex, Istubal, Valodex, Apo-Tamox, Tamofen, Altamofen
Generic name: Tamoxifen
Nolvadex is often used during Post Cycle Therapy (read more on our blog about PCT) and also to counter the effects of Gynecomastia. Nolvadex is very popular for Bodybuilders.
The chief feature of this medication is claimed to be its effectiveness in the treatment of women suffering from breast cancer. Another important feature of Tamoxifen is its approval by the FDA.
This medicine inactivates estrogen receptors. This drug prevents the binding of estrogen with the ER molecule. Thus, this preparation doesn’t allow estrogen to stimulate the growth of tumors.
Benefits of Tamoxifen
Tamoxifen is prescribed to cure persons who have certain types of breast cancers, infertility, gynecomastia, bipolar disorders, and some other illnesses. This preparation is utilized for both pre-menopausal and post-menopausal women. Since this drug has FDA approval, it has been already used by many individuals. It means that the effects of this medication are well studied. It allows physicians and patients to make informed decisions about the benefits and possible risks related to taking this product.
According to the results of different studies, this product decreases risks of breast cancer in both pre-menopausal and post-menopausal female by 50 %. Could you imagine which benefits can be obtained due to application of this preparation? It is known that this medication may reduce and even totally block development of hormone-receptor-positive breast cancer.
This medication can also decrease cholesterol level and stop bone loss after menopause.
This medication is also administrated for treatment of females who have infertility caused by ovulatory disorders. If ovulation is impeded in a woman’s body, she can’t become pregnant. Doctors prescribe Tamoxifen in order to improve ovulation. Since this medication induces egg creation in such ill women, it benefits them and helps to escape from infertility.
Dose of Tamoxifen
There is not any general dose for all persons who have various illnesses. Doctors prescribe doses of this medicine subjectively, taking in consideration all aspects that play significant roles in the situation. That’s why people must take the recommended dose strictly, not modifying it.
It is possible only to determine average dosages and common indications connected with application of this drug for treatment of different diseases. This medicine can be taken with or without meal. You have to administrate the tablets of Tamoxifen the same time each day. This principle enhances the effectiveness of this drug. You should swallow the whole tablets without crushing them. Do not drink alcoholic beverages in order to swallow tablets of this preparation.
Some females that have breast cancer may take this product for 5 years. Others administrate this drug 2-3 years, switching after administration of this product to another one which is recommended by the doctors.
Don’t take increased dosages of Tamoxifen. It may be unsafe. If you overdose, contact your doctor immediately.
Adverse results of Tamoxifen
Undesirable consequences of this medicine can affect the following systems of body:
central nervous system;
It happens that persons who use this preparation may suffer from dry skin that is claimed to be a common side effect of this medication related to dermatology.
As for the skeletal system, this drug may lead to bone pains.
This medicine can have a negative influence on reproductive system, leading to loss of libido.
Tamoxifen may also be dangerous to the central nervous system. Potential side effects of this product which are related to dysfunctions of this system are the following: headaches, depressions, fatigue, and unusual changes in mood.
Potential common negative reactions of this medication in case of digestive disorders include constipation and nausea.
Novaldex is a trade name of Tamoxifen. It may happen that your doctor may prescribe you Novaldex. So, you should know that this is the same product as Tamoxifen.
Producers of Tamoxifen
Tamoxifen is manufactured by AstraZeneca. AstraZeneca has a long history spanning more than 100 years. It produces many drugs which are used in cases of psychological dysfunctions, heart diseases, cancers, infections, respiratory troubles, digestive disorders, and others. It is also produced by Meditech and Alpha-Pharma.
Alternative medicines to Tamoxifen
Earlier, Tamoxifen was the only drug to treat females with breast cancer. Nowadays, the choice of products utilized for this need is quite broad. That’s why Tamoxifen has lost its go-to status. Since aromatase inhibitors began to be used, the situation has been totally changed. Furthermore, some medicines of the aromatase inhibitors class are claimed to be safer than Tamoxifen. Sometimes physicians advise female suffering from breast cancer to start with Tamoxifen and then to switch to Aromasin, which is also called Exemestane. It happens that doctors recommend taking Arimidex instead of Tamoxifen. Several scientists confirm that it is unsafe for females suffering from ER-positive breast cancer in the pre-menopausal period to administrate Tamoxifen. Some persons can’t utilize Tamoxifen due to clotting disorders. What can they utilize in this situation? Are there any alternatives to Tamoxifen for them? Yes, there are. They can apply Zoladex or Lupron.
It is necessary to know that lifestyle has an influence on breast cancer too. Several researches discovered a link between lifestyle, nutrition, and breast cancer. According to the data of the studies, the risk of breast cancer in women who have a sedentary lifestyle is higher than in the those who regularly engage in physical exercise. It is also known that when females eat many fruits and vegetables, they may decrease their risk of breast cancer by more than 40%.
Before using this preparation, inform your health care provider about all drugs and supplements that you use. Inform your doctor if you are pregnant or intend to become pregnant. Do not use this drug during pregnancy or while breast-feeding. Inform your physician, if you have an allergy to this product or any of its ingredients. Complete all tests that are recommended by your doctor while you are using this medicine.
Interaction of Tamoxifen with other drugs
Do not take this drug if you take such strong inhibitors as Bupropion, Paroxetine, Fluoxetine, and Duloxetine. Avoid utilizing this medication if you take MAOI inhibitors. The list of the products which cannot be taken during therapy with Tamoxifen is not full. That’s why you should speak with your doctor about any interaction of Tamoxifen with the medications you administrate.
How should you store Tamoxifen?
Store the medicine at room temperature. Keep the drug away from heat and humidity. Remember that all medicines should be stored away from the reach of children. Do not ignore these warnings.